For enhanced safety, the front and rear seat shoulder belts of the Toyota Avalon have pretensioners to tighten the seatbelts and eliminate dangerous slack in the event of a collision and force limiters to limit the pressure the belts will exert on the passengers. The Chrysler 300 doesn't offer pretensioners for the rear seat belts.

In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the Avalon are reminded to check the back seat if they opened the rear door before starting out. The 300 doesn't offer a back seat reminder.

The Toyota Avalon has standard driver and front passenger side knee airbags mounted low on the dashboard. These airbags helps prevent the driver and front passenger from sliding under their seatbelts or the main frontal airbags; this keeps them better positioned during a collision for maximum protection. Knee airbags also help keep the legs from striking the dashboard, preventing knee and leg injuries in the case of a serious frontal collision. The 300 doesn't offer a front passenger side knee airbag.

The Avalon has a standard Secondary Collision Brake, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The 300 doesn't offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.

Over 200 people are killed each year when backed over by motor vehicles. The Avalon Limited/Touring offers optional Rear Cross-Traffic Braking that uses rear sensors to monitor and automatically apply the brakes to prevent a rear collision. The 300 doesn't offer backup collision prevention brakes.

The Avalon's standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the 300 and is only available on 300 Touring L/S.

The Avalon Limited/Touring offers an optional Bird's Eye View Camera to allow the driver to see objects all around the vehicle on a screen. The 300 only offers a rear monitor and front and rear parking sensors that beep or flash a light. That doesn't help with obstacles to the sides.

The Avalon has a standard blind spot warning system which uses sensors to alert the driver to objects in the vehicle's blind spots where the side view mirrors don't reveal them. Only the 300 Touring L/S offers a blind spot warning system.

To help make backing out of a parking space safer, the Avalon has a standard cross-path warning system, which uses sensors in the rear bumper to alert the driver to vehicles approaching from the side, helping the driver avoid collisions. Only the 300 Touring L/S has a cross-path warning system.

Both the Avalon and the 300 have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, height adjustable front shoulder belts, plastic fuel tanks, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, daytime running lights and rearview cameras.

The National Highway Traffic Safety Administration does 35 MPH front crash tests on new vehicles. In this test, results indicate that the Toyota Avalon is safer than the Chrysler 300:

New test not comparable to pre-2011 test results. More stars = Better. Lower test results = Better.

A significantly tougher test than their original offset frontal crash test, the Insurance Institute for Highway Safety does 40 MPH small overlap frontal offset crash tests. In this test, where only 25% of the total width of the vehicle is struck, results indicate that the Toyota Avalon is safer than the 300:

The National Highway Traffic Safety Administration does side impact tests on new vehicles. In this test, which crashes the vehicle into a flat barrier at 38.5 MPH and into a post at 20 MPH, results indicate that the Toyota Avalon is safer than the Chrysler 300:

New test not comparable to pre-2011 test results. More stars = Better. Lower test results = Better.

For its top level performance in IIHS driver and passenger-side small overlap frontal, moderate overlap frontal, side impact, roof strength and head restraint tests, its standard front crash prevention system, and its headlight's “Good” rating, the Insurance Institute for Highway Safety grants the Avalon its highest rating: “Top Pick Plus” for 2019, a rating granted to only 103 vehicles tested by the IIHS. The 300 was not even a standard “Top Pick” for 2016.

Toyota pays for scheduled maintenance on the Avalon for 2 years and 25000 miles. Toyota will pay for oil changes, lubrication and any other required maintenance. Chrysler doesn't pay scheduled maintenance for the 300.

For smoother operation, better efficiency and fewer moving parts, the Avalon has an overhead cam design, rather than the old pushrod design of the 5.7 V8 in the 300.

J.D. Power and Associates' 2020 Initial Quality Study of new car owners surveyed provide the statistics that show that Toyota vehicles are better in initial quality than Chrysler vehicles. J.D. Power ranks Toyota 19th in initial quality. With 12 more problems per 100 vehicles, Chrysler is ranked 28th.

J.D. Power and Associates' 2021 survey of the owners of three-year-old vehicles provides the long-term dependability statistics that show that Toyota vehicles are more reliable than Chrysler vehicles. J.D. Power ranks Toyota fourth in reliability, above the industry average. With 68 more problems per 100 vehicles, Chrysler is ranked 29th.

From surveys of all its subscribers, Consumer Reports' January 2021 Auto Issue reports that Toyota vehicles are more reliable than Chrysler vehicles. Consumer Reports ranks Toyota second in reliability. Chrysler is ranked 19th.

The Avalon's 3.5 DOHC V6 produces 9 more horsepower (301 vs. 292) and 7 lbs.-ft. more torque (267 vs. 260) than the 300's standard 3.6 DOHC V6. The Avalon's 3.5 DOHC V6 produces 1 more horsepower (301 vs. 300) and 3 lbs.-ft. more torque (267 vs. 264) than the 300S' standard 3.6 DOHC V6.

As tested in Car and Driver the Toyota Avalon is faster than the Chrysler 300 V6:

On the EPA test cycle the Avalon gets better mileage than the 300:

To lower fuel costs and make buying fuel easier, the Toyota Avalon uses regular unleaded gasoline. The 300 with the 5.7 V8 engine requires mid-grade for maximum efficiency, which can cost 5 to 40 cents more per gallon.

In its Green Vehicle Guide, the U.S. Environmental Protection Agency (EPA) rates the Toyota Avalon higher (5 out of 10) than the Chrysler 300 (3). This means the Avalon produces up to 16.5 pounds less smog-producing pollutants than the 300 every 15,000 miles.

The Avalon stops shorter than the 300:

The Avalon XLE's standard tires provide better handling because they have a lower 55 series profile (height to width ratio) that provides a stiffer sidewall than the 300 Touring's standard 65 series tires. The Avalon Touring's tires have a lower 40 series profile than the 300's optional 45 series tires.

The Avalon offers an available driver-adjustable suspension system. It allows the driver to choose between an extra-supple ride, reducing fatigue on long trips, or a sport setting, which allows maximum control for tricky roads. The 300's suspension doesn't offer adjustable shock absorbers.

The Avalon Touring handles at .85 G's, while the 300 pulls only .82 G's of cornering force in a Car and Driver skidpad test.

The Avalon Touring executes Motor Trend's “Figure Eight” maneuver quicker than the 300 (26.8 seconds vs. 27.2 seconds).

The Toyota Avalon may be more efficient, handle and accelerate better because it weighs about 450 to 650 pounds less than the Chrysler 300.

The design of the Toyota Avalon amounts to more than styling. The Avalon has an aerodynamic coefficient of drag of .27 Cd. That is significantly lower than the 300 (.32) and many sports cars. A more efficient exterior helps keep the interior quieter and helps the Avalon get better fuel mileage.

The Avalon Touring uses computer-generated active noise cancellation to help remove annoying noise and vibration from the passenger compartment, especially at low frequencies. The 300 doesn't offer active noise cancellation.

The Avalon has .3 inches more front legroom and .2 inches more rear legroom than the 300.

The Avalon Limited/Touring has a standard heads-up display that projects speed, tachometer, warning and navigation instruction readouts in front of the driver's line of sight, allowing drivers to view information without diverting their eyes from the road. The 300 doesn't offer a heads-up display.

The Avalon's power parking brake sets with one touch and releases with one touch or automatically. The 300's parking brake has to released manually.

The Avalon's front and rear power windows all open or close fully with one touch of the switches, making it more convenient at drive-up windows and toll booths, or when talking with someone outside the car. The 300's rear power window switches have to be held the entire time to open or close them fully.

If the windows are left open on the Avalon the driver can close them all at the outside door handle. On a hot day the driver can lower the windows at the outside door handle or from a distance using the keyless remote. (This window function must be activated by your Toyota service department.) The driver of the 300 can only close the windows from inside the vehicle, with the ignition on.

The Insurance Institute for Highway Safety (IIHS) conducts detailed tests on headlights for their range both straight ahead and in curves and to be certain they don't exceed acceptable amounts of glare to oncoming drivers. The Avalon's available headlights were rated “Good” by the IIHS, while the 300's headlights are rated “Poor.”

The Avalon will cost the buyer less in the long run because of its superior resale value. The IntelliChoice estimates that the Avalon will retain 41.63% to 42.3% of its original price after five years, while the 300 only retains 36.68% to 39.61%.

According to The Car Book by Jack Gillis, the Avalon is less expensive to operate than the 300 because typical repairs cost much less on the Avalon than the 300, including $1417 less for a muffler, $10 less for front brake pads, $520 less for front struts and $638 less for a power steering pump.

IntelliChoice estimates that five-year ownership costs (depreciation, financing, insurance, fuel, fees, repairs and maintenance) for the Toyota Avalon will be $525 to $8160 less than for the Chrysler 300.

The Toyota Avalon has won recognition from these important consumer publications: